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GWB may refer to:
- Baylor University Golden Wave Band
- DeKalb County Airport (Indiana)
- The Geochemist's Workbench, a scientific modelling suite
- George Warren Brown School of Social Work of Washington University in St. Louis
- George Washington Bridge, linking Washington Heights, Manhattan to Fort Lee, New Jersey, United States
- George W. Bush (born 1946), 43rd President of the United States
- Gravitational wave background
- Great Western Bank (1907–present), an American bank
- gwb ISO code for the Gwa language
- Gypsum wall board, a.k.a. drywall, a construction material
| disambiguation page lists articles associated with the title GWB.
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